CDCAR1 is a deleted in breast cancer 1 (DBC1) domain containing protein and their molecular roles in the animal system are well characterized. So far study on CDCAR1 protein not available in plant system. SMART domain based phylogenetic study clearly indicated that the CDCAR1 protein widely distributed throughout the plant Kingdome. Intron-less CDCAR1 gene encoded protein comprises five conserved domain and huge intrinsic disorder. Functional annotation of cis-regulatory elements (CREs) revealed that a wide range of potential transcription factor binding sites (TFBSs) are present in CDCAR1 gene promoter. Beside that potential miRNA targets those control post-transcriptional regulation also identified in the present study. Our gene ontogeny (GO) analysis revealed that CDCAR1 have dynamics role in cellular and metabolic processes. In this study we first report the regulation, functional and structural property of CDCAR1 transcript and protein which will may help to assist crop improvement by manipulating CDCAR1.
Raju Mondal and Poushali Das