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Abstract

Evaluation of Some Trace Elements in Streptozocin Induced Diabetic Rats Treated with Moringa Oleifera Leaf Powder

This work was done to determine the trace elements in strreptozocin-induced diabetic rats treated with moringa oleifera leaf. This was conducted using 5 groups of 10 rats each were used. Group1 negative control, group2 positive control (diabetics), groups 3 and 4 treated with 150mg/kg and 300mg/kg of moringa oleifera leaf respectively.The parameters analysed includes; zinc, copper, selenium manganese. P. values p<0.05 were considered statistically significant. The study showed that there was a significant increasein the magnesium levels of rats in groups 4(0.047±0.19) when compared with groups 1 and 2 (0.19±0.14 and 0.13±0.37), there was a significant increase (P <0.05) in the zinc levels of rats in groups 4(0.58± 0.08) when compared with that of groups 1 and 2(0.30±0.15 and 0.39±0.05),there was a significant increase in the selenium levels of rats in group 2 (7.51±1.79) when compared with those in groups 1, 3 and 4(6.43±1.21, 6.30±1.51 and 6.30±1.11). Also there was no significant difference in the Cu levels of rats in all the groups. From this study, it could be inferred that moringa oleifera leaf powder used in treatment of streptozocin-induced diabetes in rats reduced the toxic damage to the kidney and liver.


Author(s):

Arvin Nwakuilite, Nwanjo HU, Nwosu DC and Emmanuel Ifeanyi Obeagu*



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